Source: CURATED ×
| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
| STK11 | Q15831 | serine/threonine kinase 11 | Kinase | 0.99 | 0.435 | 0.808 |
| SMARCA4 | P51532 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | Epigenetic regulator | 1.00 | 0.450 | 0.885 |
| RRAS2 | P62070 | RAS related 2 | Enzyme modulator | 0.97 | 0.656 | 0.500 |
| RNF43 | Q68DV7 | ring finger protein 43 | 0.73 | 0.584 | 0.577 | |
| PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
| PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
| PMS1 | P54277 | PMS1 homolog 1, mismatch repair system component | Nucleic acid binding | 1.3E-17 | 0.569 | 0.654 |
| PIK3R1 | P27986 | phosphoinositide-3-kinase regulatory subunit 1 | Kinase | 1.00 | 0.477 | 0.885 |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| OPCML | Q14982 | opioid binding protein/cell adhesion molecule like | 0.23 | 0.606 | 0.654 | |
| MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
| MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
| MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
| MAP2K1 | Q02750 | mitogen-activated protein kinase kinase 1 | Kinase | 0.90 | 0.439 | 0.846 |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
| ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
| ERCC6 | P0DP91 Q03468 | ERCC excision repair 6, chromatin remodeling factor | 5.2E-22 | 0.507 | 0.808 | |
| ERCC4 | Q92889 | ERCC excision repair 4, endonuclease catalytic subunit | Enzyme | 1.4E-12 | 0.468 | 0.846 |
| ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
| CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
| CDK12 | Q9NYV4 | cyclin dependent kinase 12 | Kinase | 1.00 | 0.638 | 0.462 |
| CCNE1 | P24864 | cyclin E1 | Enzyme modulator | 0.97 | 0.538 | 0.731 |
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
| BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |